Endocrine Abstracts

There is a marked disparity between the amount of androstenedione (A) excreted in the urine as testosterone (T) glucuronide and the amount of A-T converted in the systemic circulation indicating that there is considerable production of testosterone within the portal circulation which is extracted by the liver. Our studies have examined the hypothesis that intra-abdominal fat is a major source of testosterone production which might contribute to insulin resistance.<p class=...